Tramadol - Revision history

Byte at 16:52, 25 January 2026

2026-01-25T16:52:34Z

← Older revision		Revision as of 16:52, 25 January 2026
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	== Available forms ==		== Available forms ==

	* 10 mg tablet		* 10 mg tablet {{Pill icon\|tablet}}
	* 20 mg tablet		* 20 mg tablet {{Pill icon\|tablet}}
	* 20 mg extended release tablet		* 20 mg extended release tablet {{Pill icon\|er}}
	* 50 mg extended release tablet		* 50 mg extended release tablet {{Pill icon\|er}}
	* 10 mg/mL injection solution		* 10 mg/mL injection solution {{Pill icon\|vial}}
	* 20 mg/mL injection solution		* 20 mg/mL injection solution {{Pill icon\|vial}}

	== Pharmacokinetics ==		== Pharmacokinetics ==

Byte at 08:28, 25 January 2026

2026-01-25T08:28:54Z

← Older revision		Revision as of 08:28, 25 January 2026
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	== Description ==		== Description ==

	TODO		{{TODO}}

	== Indications ==		== Indications ==

	* TODO		{{TODO}}

	== Administration Routes ==		== Administration Routes ==
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	== Side Effects ==		== Side Effects ==

	* TODO		{{TODO}}

	== Dosage ==		== Dosage ==
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	== Interactions ==		== Interactions ==

	TODO		{{TODO}}

	== Notes ==		== Notes ==

	A serum concentration of 100-300 ng/ml is usually effective for analgesia.		A serum concentration of 100-300 ng/ml is usually effective for analgesia.

Byte at 08:11, 25 January 2026

2026-01-25T08:11:55Z

← Older revision		Revision as of 08:11, 25 January 2026
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	== Administration Routes ==		== Administration Routes ==

	* [[Oral administration\|Oral]]{{~~#set: Supports administration method~~=~~oral}}~~		{{Administration routes\|o=y\|im=y\|iv=y}}
	* [[Intravenous administration\|~~Intravenous (IV)]]{{#set: Supports administration method~~=~~intravenous}}~~
	* [[Intramuscular administration\|~~Intramuscular (IM)]]{{#set: Supports administration method~~=~~intramuscular~~}}

	== Side Effects ==		== Side Effects ==

Byte at 07:50, 25 January 2026

2026-01-25T07:50:00Z

← Older revision		Revision as of 07:50, 25 January 2026
Line 12:		Line 12:
	== Administration Routes ==		== Administration Routes ==

	* [[Oral administration\|Oral]]		* [[Oral administration\|Oral]]{{#set: Supports administration method=oral}}
	* [[Intravenous administration\|Intravenous (IV)]]		* [[Intravenous administration\|Intravenous (IV)]]{{#set: Supports administration method=intravenous}}
	* [[Intramuscular administration\|Intramuscular (IM)]]		* [[Intramuscular administration\|Intramuscular (IM)]]{{#set: Supports administration method=intramuscular}}

	== Side Effects ==		== Side Effects ==

Byte: Created page with "Category:Medications Category:Analgesics Category:Opioids == Description == TODO == Indications == * TODO == Administration Routes == * Oral * Intravenous (IV) * Intramuscular (IM) == Side Effects == * TODO == Dosage == For acute pain: * 0.75-1.5 mg/kg IM or IV every 4-6 hours * Dosage should be adjusted according to pain severity and response * IV push must be g..."

2026-01-25T06:59:26Z

Created page with "Category:Medications Category:Analgesics Category:Opioids == Description == TODO == Indications == * TODO == Administration Routes == * Oral * Intravenous (IV) * Intramuscular (IM) == Side Effects == * TODO == Dosage == For acute pain: * 0.75-1.5 mg/kg IM or IV every 4-6 hours * Dosage should be adjusted according to pain severity and response * IV push must be g..."

New page

[[Category:Medications]]
[[Category:Analgesics]]
[[Category:Opioids]]
== Description ==

TODO

== Indications ==

* TODO

== Administration Routes ==

* [[Oral administration|Oral]]
* [[Intravenous administration|Intravenous (IV)]]
* [[Intramuscular administration|Intramuscular (IM)]]

== Side Effects ==

* TODO

== Dosage ==

For acute pain:

* 0.75-1.5 mg/kg IM or IV every 4-6 hours
* Dosage should be adjusted according to pain severity and response
* IV push must be given slowly over 2-3 minutes

For post-operative pain:

* Initial 1.5 mg/kg slow IV push.
* Over the next hour, further doses of 0.75 mg/kg may be given every 10-20 minutes.
** (Up to a total dose of 3.75 mg, including the initial bolus)
* After 1 hour, subsequent doses should be 0.75-1.5 mg/kg every 4-6 hours.

Maximum daily dose should not exceed 6 mg/kg/day.

== Available forms ==

* 10 mg tablet
* 20 mg tablet
* 20 mg extended release tablet
* 50 mg extended release tablet
* 10 mg/mL injection solution
* 20 mg/mL injection solution

== Pharmacokinetics ==

The following table is only an approximation, for single doses. Tramadol has a predominantly linear pharmacokinetic profile within the therapeutic dosage range, partially due to production of active metabolite M1.

{| class="wikitable" style="margin:auto"
|-
! Route
! Onset
! Peak
! t<sub>1/2</sub>β
! Duration of action
|-
| IV
| Seconds
| Immediate
| rowspan="3" | 5-6 hours
| 4-8 hours
|-
| IM
| 10-20 mins
| 45 mins
| 4-8 hours
|-
| O
| 60 mins
| 2-3 hours
| 6 hours
|-
| O (ER)
| 2-4 hours
| 6-8 hours
| 8-10 hours
| 10-14 hours
|}

Oral bioavailability: 75%

== Interactions ==

TODO

== Notes ==

A serum concentration of 100-300 ng/ml is usually effective for analgesia.