Byte: Created page with "Category:Medications Category:Anticoagulants == Description == Heparin is a sulfated polysaccharide anticoagulant that increases the activity of antithrombin. == Indications == * heart attack * unstable angina * reversal of procoagulant action == Administration Routes == {{Administration routes|iv=y|im=y|sc=y}} == Side Effects == * bleeding * pain at the injection site * low blood platelets == Dosage == For anticoagulation:..."

2026-01-28T05:04:03Z

Created page with "Category:Medications Category:Anticoagulants == Description == Heparin is a sulfated polysaccharide anticoagulant that increases the activity of antithrombin. == Indications == * heart attack * unstable angina * reversal of procoagulant action == Administration Routes == {{Administration routes|iv=y|im=y|sc=y}} == Side Effects == * bleeding * pain at the injection site * low blood platelets == Dosage == For anticoagulation:..."

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[[Category:Medications]]
[[Category:Anticoagulants]]
== Description ==

Heparin is a sulfated polysaccharide [[:Category:Anticoagulants|anticoagulant]] that increases the activity of antithrombin.

== Indications ==

* heart attack
* unstable angina
* reversal of procoagulant action

== Administration Routes ==

{{Administration routes|iv=y|im=y|sc=y}}

== Side Effects ==

* bleeding
* pain at the injection site
* low blood platelets

== Dosage ==

For anticoagulation:

* 150 units/kg IV push
** Maintain as needed with 100 units/kg every 4-6 hours

== Available forms ==

* Prefilled syringe 2000 units / 2 mL (1000 units/mL) {{Pill icon|syringe}}
* Prefilled syringe 5000 units / 5 mL (5000 units/mL) {{Pill icon|syringe}}

== Pharmacokinetics ==

{{TODO}}

{| class="wikitable" style="margin:auto;text-align:center;"
! Route !! Onset !! Peak !! Half-life !! Duration of action
|-
| IV || Immediate || Immediate || 1-2 hours || 1-2 hours
|-
| SC || 1-2 hours || 3 hours || 1-2 hours || 1-2 hours
|-
| IM || ? || ? || ? || ?
|}

Note: heparin metabolism is quickly saturated and has predominantly linear elimination kinetics.

== Interactions ==

{{TODO}}

Heparin - Revision history